To understand the genomic basis of ash tree susceptibility to ash dieback (Hymenoscyphus fraxineus) we have undertaken population genomic studies. This data has been analysed in the frameworks of genome-wide association studies and genomic prediction. Several thousand genetic loci associated with susceptibility to ash dieback have been identified.
More details of this work can be found in the following papers:
Jonathan J. Stocks, Carey L. Metheringham, William Plumb, Steve J. Lee, Laura J. Kelly, Richard A. Nichols and Richard J. A. Buggs (2019) Genomic basis of European ash tree resistance to ash dieback fungus. Nature Ecology & Evolution 3: 1686–1696 Full text
Carey L. Metheringham, William J. Plumb, Jonathan J. Stocks, Laura J. Kelly, Miguel Nemesio Gorriz, Justin Moat, Richard J. A. Buggs, Richard A. Nichols (2022) Rapid polygenic adaptation in a wild population of ash trees under a novel fungal epidemic bioRxiv Full text
Raw reads from our population studies are available as follows:
| Species | Description | Reads on ENA | Publication |
| Fraxinus excelsior | Diversity Panel (37 trees from across Europe, 8.4X coverage) | Project: PRJEB4958 Samples: ERS1205907-ERS1205943 Experiments: ERX1527454; ERX1527519- ERX1527532; ERX1527545- ERX1527554; ERX1527557- ERX1527568; ERX1527570- ERX1527606 | Sollars et al (2017) Nature |
| Fraxinus excelsior | 31 Pools (80X coverage) from 1250 trees | Project: PRJEB31096 | Stocks et al (2019) Nature Ecology & Evolution |
| Fraxinus excelsior | 150 individuals (20X coverage) | Project: PRJEB31096 | Stocks et al (2019) Nature Ecology & Evolution |
| Fraxinus excelsior | 660 individuals (Marden Park Wood) | Project: PRJEB44697 (ERP128769) | Metheringham et al (2022) BioRxiv |