Photo of ash woodland

Population genomics

To understand the genomic basis of ash tree susceptibility to ash dieback (Hymenoscyphus fraxineus) we have undertaken population genomic studies. This data has been analysed in the frameworks of genome-wide association studies and genomic prediction. Several thousand genetic loci associated with susceptibility to ash dieback have been identified.

More details of this work can be found in the following papers:

Jonathan J. Stocks, Carey L. Metheringham, William Plumb, Steve J. Lee, Laura J. Kelly, Richard A. Nichols and Richard J. A. Buggs (2019) Genomic basis of European ash tree resistance to ash dieback fungus. Nature Ecology & Evolution 3: 1686–1696 Full text

Carey L. Metheringham, William J. Plumb, Jonathan J. Stocks, Laura J. Kelly, Miguel Nemesio Gorriz, Justin Moat, Richard J. A. Buggs, Richard A. Nichols (2022) Rapid polygenic adaptation in a wild population of ash trees under a novel fungal epidemic bioRxiv Full text

Raw reads from our population studies are available as follows:

SpeciesDescriptionReads on ENAPublication
Fraxinus excelsiorDiversity Panel (37 trees from across Europe, 8.4X coverage)Project: PRJEB4958 Samples: ERS1205907-ERS1205943 Experiments: ERX1527454; ERX1527519- ERX1527532; ERX1527545- ERX1527554; ERX1527557- ERX1527568; ERX1527570- ERX1527606Sollars et al (2017) Nature  
Fraxinus excelsior31 Pools (80X coverage) from 1250 treesProject: PRJEB31096Stocks et al (2019) Nature Ecology & Evolution
Fraxinus excelsior150 individuals (20X coverage)Project: PRJEB31096Stocks et al (2019) Nature Ecology & Evolution
Fraxinus excelsior660 individuals (Marden Park Wood)Project: PRJEB44697 (ERP128769)Metheringham et al (2022) BioRxiv